non-randomized controlled trial
A study comparing interventions in which the allocation of participants to the control and intervention groups is not based on chance.
Note 1: Examples include allocation based on alternating groups, the investigator’s practical constraints, or the participant’s choice.
Note 2: A non-randomized controlled trial is different from an observational study and a non-experimental study.
Note 3: Synonyms include nonrandomized controlled trial, nonrandomized comparative study or trial, nonrandomized intervention study or trial, non-randomized clinical trial.
Note 4: Related terms include quasi-randomized clinical trial, quasi-experimental clinical trial, pseudo-randomized trial, and controlled clinical trial.